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A-Level BiologyYear 2022Q4

10   4 Malaria is a disease that kills more than 400 000 people every year. It is caused by Plasmodium, a single-celled organism that lives in the blood. Plasmodium is transmitted by mosquitoes. The diagram shows a Plasmodium organism. (a) State and justify two structures shown in the diagram that indicate that Plasmodium is a eukaryotic organism. (2) .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... Turn over 11   (b) Malaria can be controlled by killing the mosquitoes that transmit the disease. Scientists are genetically modifying Metarhizium pingshaense, a fungus that infects mosquitoes. The genetically modified (GM) fungus contains a gene from a species of spider. This gene codes for a protein that kills mosquitoes. (i) The GM fungus transcribes and translates the gene for this protein. Describe the primary structure of a protein. (2) .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... (ii) The primary structure of this protein is then converted into a tertiary structure and modified by organelles in the cell. Describe the role of the organelles involved in these processes. (5) .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... .................................................................................................................................................................................................................................................................................... (Total for Question 4 = 9 marks)

Paper Source:9bn0-01-que-20220610.pdf

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Exam Specification Info

This question is part of the UK A-Level Biology syllabus. In the actual exam, structured questions typically require linking specific keywords to gain full marks. Applaa helps you drill these topics.

Syllabus levelAdvanced Level (A-Level)
SubjectBiology
Official MarksVariable (2–6 marks)